Showing posts from March, 2018

Some important phytochemicals from Yashtimadhu-Licorice (Glycyrrhiza glabra)

Some important phytochemicals from Yashtimadhu-Licorice (Glycyrrhiza glabra) By Dr. Hemant Vinze  (M. S.) Introduction Yashtimadhu-licorice ( Glycyrrhiza glabra ) is used mainly for the treatment of pharyngitis, laryngitis, respiratory diseases such as bronchitis; GI conditions such as gastritis (hyperacidity) and in many polyherbal medicinal formulations. Yashtimadhu-licorice ( Glycyrrhiza glabra ), in fact, exhibits pleotropic pharmacological activity. Needless to say this is due to many pharmacologically active phytochemicals contained in it. In this article I present a few important pharmacologically active phytochemicals from Yashtimadhu-licorice ( Glycyrrhiza glabra ).   Glabrol Molecular formula:  C25H28O4 Structural formula:    Glabrol is an acyl-coenzyme A. It is isolated from the roots of yashtimadhu-licorice ( Glycyrrhiza glabra ). Cholesterol acyltransferase esterifies free cholesterol in the liver and the intestine. Accumulation of these es